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Sartorius Biostat® B Bioreactor

Sartorius Biostat® B Bioreactor

winselluma is an authorized distributor offering the Sartorius Biostat® B Bioreactor, a reliable solution designed for efficient scale-up and flexible process development. This bioreactor combines precise process control with user-friendly operation, supporting a wide range of bioprocess applications. With winselluma’s commitment to quality and customer support, you can trust seamless integration and dependable performance. Enhance your bioprocessing capabilities with a partner that values excellence and innovation.

  • Product Info

    The Biostat® B is a versatile, high-performance benchtop bioreactor and fermenter designed for both research and small-scale production. It is engineered to support a wide range of applications, including mammalian cell culture, microbial fermentation, and the development of vaccines and cell therapies.

     

    Flexible Configuration and Scalability

    • Dual-Use Capability: The system is available in two primary formats:

      • Single-Use: Compatible with UniVessel® SU bioreactors (500 mL to 2 L), minimizing cleaning and sterilization downtime.

      • Autoclavable: Compatible with traditional glass UniVessel® units (1 L to 5 L) for reusable, cost-effective laboratory workflows.

    • Multi-Vessel Control: A single control tower can manage up to two culture vessels independently, allowing for parallel experimentation and process optimization within a compact footprint.

    • Process Transfer: Designed with geometric similarity to the larger Biostat® STR series, ensuring that parameters developed on the benchtop can be scaled up to 2,000 L production volumes.

    Advanced Control and Monitoring

    • Integrated DCU Controller: Features a high-resolution touchscreen interface for real-time monitoring of pH, dissolved oxygen (DO), temperature, and agitation.

    • Precision Gas Management:

      • Equipped with up to four integrated mass flow controllers (MFC) per vessel.

      • Supports various aeration strategies (O2 enrichment, CO2 stripping, and N2 sparging) to maintain optimal gas transfer rates.

    • Integrated Pumps: Each control unit includes up to four peristaltic pumps for precise nutrient feeding, acid/base titration, and foam control.

    • External Integration: Features analog and digital I/O ports for connecting external sensors, scales, or BioPAT® analytical tools (such as Raman spectroscopy or viable cell density sensors).

    Technical Features

    • Agitation: High-torque motors support a wide speed range, accommodating both the low-shear requirements of sensitive animal cells and the high oxygen demands of rapid microbial growth.

    • Temperature Control: Utilizes an integrated heating blanket or a cooling finger/coil system for precise thermal management between 8°C above coolant temperature and 80°C.

    • Automation Ready: Fully compatible with BioPAT® MFCS software for data logging, batch reporting, and advanced process control (APC).

    Common Applications

    • Process Development: Rapid optimization of media, feeding strategies, and environmental parameters.

    • Cell Line Characterization: Studying the growth kinetics of CHO, HEK293, and insect cell lines.

    • Microbial Fermentation: High-density cultivation of E. coli, yeast, and fungi.

    • Small-Scale Production: Ideal for generating material for preclinical trials or specialized bioproducts.

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